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            <h2 class="font-medium">Qiming Monthly Newsletter (September 2022) </h2>
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          <span class="date-display-single">09/10/2022</span>    
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<p class="rtejustify">&nbsp;</p>

<p><span style="color:#e74c3c;"><span style="font-size:22px;">Deals</span></span></p>

<p><strong><span style="font-size:18px;">Financing</span></strong></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Ailomics Therapeutics</strong>, a pharmaceutical R&amp;D startup founded in 2022, announced that it raised tens of millions of RMB in the angel round led by Qiming Venture Partners. The firm plans to use the fresh funds to build core technology platform and advance R&amp;D pipeline.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Koutech</strong>, an ultra-micro and high-precision surgical robot platform company, raised hundreds of millions of RMB in series A funding led by Qiming Venture Partners. The funding will support R&amp;D, team building, GMP plant construction, etc.</span></p>

<p>&nbsp;</p>

<p><span style="color:#e74c3c;"><span style="font-size:22px;">Portfolio Highlights</span></span></p>

<p><strong><span style="font-size:18px;">Milestones</span></strong></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;">Dr. Xuefeng Yu, Co-Founder, CEO and Chairman of <strong>CanSino Biologics</strong> (SEHK:6185, SHSE:688185) talked exclusively with Bloomberg on the new Convidecia Air™ and its development process, discussing the world's first inhaled Covid vaccine approved for use.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;">China's NMPA has officially approved ripertamab injection, the novel anti-CD20 mAb developed by <strong>SinocellTech</strong> (SHSE: 688520), to be used in combination with standard CHOP chemotherapy in adult patients with newly diagnosed CD20-positive diffuse large B-cell non-Hodgkin lymphoma (DLBCL) with an International Prognostic Index (IPI) of 0 to 2.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>CanSino Biologics</strong> (SEHK:6185, SHSE:688185) announced that China's NMPA has granted approval for its Recombinant COVID-19 Vaccine (Adenovirus Type 5 Vector) for Inhalation (trade name: Convidecia Air™) to be used as a booster dose.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Insta360</strong> recently launched X3, a powerful 360 action camera that helps capture creative and unique content for social media, powered by 1/2″ 48MP sensors and 2.29″ touchscreen.&nbsp;</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Roborock</strong> (SHSE: 688169), ranks first among robot vacuum makers globally in terms of sales of high-end models for 12 months from July 2021 to June 2022, according to Euromonitor. Roborock also launched its latest A10 series in China.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Bondent Group</strong> recently presented Semorr Naked Eye 3D Microscope, Semorr G4 Microscope, UDG Platinum VEU Files, as well as Wismy Endo Motor at the European Society of Endodontology (ESE).</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;">Global leading open metaverse platform <strong>BUD</strong> launched a crossover collaboration with NetEase Games' iconic game Never After, providing customized crossover Avatars and various theme activities for BUD users.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Antengene</strong> (SEHK: 6996) announced that ATG-101, the company's in-house developed novel PD-L1/4-1BB bispecific antibody, has been granted an Orphan Drug Designation by the U.S. Food and Drug Administration for the treatment of pancreatic cancer.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>OriCell Therapeutics</strong> has formally received an implied license from China's NMPA for its Ori-C101 Investigational New Drug application.</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;">Global leading biopharmaceutical company <strong>Zai Lab</strong> (NASDAQ:ZLAB, SEHK:9688) and Seagen, a world leader and pioneer in antibody-drug conjugate (ADC) therapies announced a strategic partnership and license agreement for the development and commercialization of TIVDAK (tisotumab vedotin-tftv) in mainland China, Hong Kong, Macau, and Taiwan.</span></p>

<p><strong><span style="font-size:18px;">Awards</span></strong></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>2022 Fortune China Best Designs List</strong> - UBTECH Robotics, Mech-Mind Robotics, NEIWAI &nbsp;</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Forbes China Global 100 Outstanding Chinese list</strong> - Wang Xiang, Partner and President of Xiaomi Technology (SEHK:1810), Song Mingyang, CEO of International Business at Meitu (SEHK:1357)</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Hong Kong Business Technology Excellence Awards 2022</strong> in the AI - Pharmaceuticals category - Insilico Medicine</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>2022 PharmaVoice 100 List</strong> - Raymond Stevens, CEO and Founder of <strong>Structure Therapeutics</strong>, and Samantha Du, Chairperson and Chief Executive Officer of <strong>Zai Lab</strong> (NASDAQ:ZLAB, SEHK:9688)</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>TOP 100 China Pharmaceutical Innovative Enterprises</strong> by Healthcare Executive - Zai Lab (NASDAQ:ZLAB, SEHK:9688), SinocellTech (SHSE: 688520), Antengene (SEHK:6996), Jacobio Pharma (SEHK:1167), CanSino Biologics (SEHK:6185, SHSE:688185), InventisBio (SHSE: 688382), Genor BioPharma (SEHK:6998), Abbisko Therapeutics (SEHK:2256), Asieris Pharmaceuticals (SHSE: 688176), ACEA Therapeutics</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>TOP 100 China Pharmaceutical Innovative Emerging Enterprises</strong> by Healthcare Executive - LaNova Medicines, Suzhou Abogen Biosciences, Shenogen Pharma, Connect Biopharma (NASDAQ: CNTB), Newsoara, Kechow Pharma, Arkbio</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;">China's Home Market TOP 10 Best Return Star Cases of <strong>2022 Investment Institution Series Lists</strong> by 36Kr - <strong>Tigermed</strong> (SZSE:300347, SEHK:3347)</span></p>

<p>&nbsp;</p>

<p><span style="color:#e74c3c;"><span style="font-size:22px;">Qiming Updates</span></span></p>

<p><strong><span style="font-size:18px;">Insights</span></strong></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;">“We have witnessed a lot of investments in drug discovery, diagnostics, devices, tech, and so forth. There are still a lot of opportunities when investing in the infrastructure of companies,” said <strong>Nisa Leung</strong>, Managing Partner of Qiming Venture Partners, at the sidelines of the HKEX Biotech Summit on Bloomberg.</span></p>

<p><strong><span style="font-size:18px;">Events</span></strong></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Grace Lee</strong>, Partner and the Group COO of Qiming Venture Partners, will participate in the 35th Annual Asian Venture Capital Journal Forum among other leading expert speakers. They will share expertise in deal sourcing, fundraising, the buyout and secondaries markets, exits, ESG, and more.</span></p>

<p><strong><span style="font-size:18px;">Awards</span></strong></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>2021 Leader of the Year</strong> in the Commerce &amp; Industry/Finance category by Sing Tao News Corporation Limited - <strong>Nisa Leung</strong></span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>2022 Yicai Equity Investment Value List</strong> - TOP 50 Investment Institution; Outstanding Female Investor - <strong>Nisa Leung&nbsp;</strong></span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Global Venture Capitalists 2022 Half-Year Report</strong> - TOP 4 Investment Institution Founded in China, and 24th globally</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>21st Century Private Equity and Venture Capital Competitiveness Study and Ranking</strong> by 21st Century Business Herald - TOP 30 VC and PE Institutions</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>The 2021-2022 China PE/VC Industry Awards</strong> - TOP 20 China's Venture Capital Institutions, TOP 10 ESG Institutions in China's Equity Investment Industry, TOP 20 Active Investment Institutions in China's Healthcare Industry, TOP 20 Active Investment Institutions in the Artificial Intelligence Industry, TOP 20 Active Investment Institutions in the Advanced Manufacturing Industry</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>2022 Investment Institution Series Lists</strong> by 36Kr - TOP 4 in China's TOP 50 Venture Capital Voted by Limited Partners; China's Home Market TOP 10 Best Return Fund - Qiming's RMB Fund I</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Cyzone</strong> - 2022 Most Admired Venture Capital Firms in China and No.1 Healthcare Industry Investment Firm; 2022 ESG Best Practice Award for China VC Firms</span></p>

<p><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:16px;"><strong>Golden Investment Mid-year Prize List of CVCRI 2022 China Venture Capital Annual List</strong> - China Influence Investment Institution, China's Best Internet/Mobile Internet Investment Institution; China's Best Investment Institution in Healthcare</span></p>

<p>&nbsp;</p>

<p><span style="color:#7f8c8d;"><span style="font-size:16px;">Sources: Qiming Venture Partners, company press releases, media reports, etc.</span></span><br />
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