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            <h2 class="font-medium">Qiming Monthly Newsletter (February 2023)</h2>
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          <span class="date-display-single">03/03/2023</span>    
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          <p><img alt="" src="/sites/default/files/230303-2.jpg" style="width: 1274px; height: 543px;" /></p>

<p><span style="color:#e74c3c;"><span style="font-size:22px;">Qiming Updates</span></span></p>

<p><strong><span style="font-size:18px;">Insights</span></strong></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Following on Hesai Technology (NASDAQ: HSAI)'s successful IPO on Nasdaq, <b>Founding Managing Partner Duane Kuang</b> highlighted Qiming Venture Partners' strategy in investing in the entire industry ecosystem. Qiming will continue to explore opportunities in the upstream and downstream of smart mobility and autonomous driving. “As a VC firm, we should understand the needs of tech startups and become a long-term backer.” </span></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Partner Kuantai Yeh</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> shared his thoughts on one of Yicai Words of the Year in 2022 – hard technology. He understood the term more as service to enterprise customers than consumer products and shared key factors in making investment decisions in this area: team, product, market and capital. He emphasized the essence of hard technology is science and innovation, which needs to cultivate world-class talents.</span></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Qiming Venture Partners'<b> Partner Alex Zhou</b> shared his understanding of generative AI and future VC investment opportunities in this area. He believed that the real capability of AI is not limited to painting and chatting but being integrated into the industry workflow and providing higher business value.</span></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Speaking of investment philosophy trends in healthcare, our <b>Partner Kan Chen</b> shared that life science innovation should bring clinical value, and investments are focusing more on startups' global competitiveness. More interdisciplinary approaches between healthcare and other technologies, as well as a greater emphasis on scale and efficiency are trends to watch.</span></span></span></p>

<p><strong><span style="font-size:18px;">Awards</span></strong></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">2022 Annual Global League Tables</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>PitchBook</i> - TOP3 Most Active&nbsp;VC&nbsp;in Greater China, TOP21&nbsp;Most Active VC at Early Stage Globally, TOP4 Most Active VC in HC Devices &amp; Supplies, TOP5 Most Active VC in Pharma &amp; Biotech, TOP10 Most Active VC in IT Hardware, and TOP21 Most Active VC in HC Services &amp; Systems <b>(</b></span><a href="https://pitchbook.com/news/articles/global-league-tables-2022-annual?utm_medium=nl-%5b%E2%80%A6%5dorts&amp;utm_campaign=2022-annual-interactive-global-league-tables" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">Read More</span></b></a><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">)</span></b></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Private Equity Association of Shanghai (PEAS) 2022 Annual Equity Investment List</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> - Best Investment Institution, Most Active Investment Institution, and Best Exit Investment Institution - <b>Qiming Venture Partners</b>; Best Investor of the Year - <b>Duane Kuang</b>; Best Healthcare Investor - <b>William Hu</b>; Best Investor in the IT industry - <b>Kuantai Yeh</b>; Best Investor in the Consumer industry - <b>Bonnie Wang</b>; Best Investor in the Advanced Manufacturing Industry - <b>Nan Chen</b>; Future Stars - <b>Yi Tang</b></span></span></span></p>

<p align="left" style="text-align:left; margin:0cm"><span style="font-size:10.5pt"><span style="font-family:DengXian">&nbsp;</span></span></p>

<p><span style="color:#e74c3c;"><span style="font-size:22px;">Portfolio Highlights</span></span></p>

<p><strong><span style="font-size:18px;">ESG</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">LanzaTech</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (NASDAQ: LNZA)'s project "RESTORE: Replenishing EcoSystems by Transforming Residues to Energy" was selected by the U.S. Department of Energy (DOE) to accelerate the production of sustainable biofuels for America's transportation and manufacturing needs. </span><a href="https://www.energy.gov/eere/bioenergy/articles/us-department-energy-awards-118-million-accelerate-domestic-biofuel" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p><strong><span style="font-size:18px;">IPO</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">LanzaTech </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(NASDAQ: LNZA), an innovative leader in carbon capture and transformation, listed on Nasdaq on February 10 Beijing Time via SPAC merger. </span><a href="https://medium.com/@QimingVenturePartners/qiming-venture-partners-portfolio-company-lanzatech-lists-on-nasdaq-11a007c46753" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Hesai Technology</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (NASDAQ: HSAI), a global leader in LiDAR technology, began trading on Nasdaq. </span><a href="https://medium.com/@QimingVenturePartners/qiming-venture-partners-celebrates-hesai-technologys-ipo-on-nasdaq-bcdd4f3fa875" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Structure Therapeutics</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (NASDAQ: GPCR), a clinical stage global biopharmaceutical company focusing on novel oral small molecule therapeutics, successfully debuted on Nasdaq on February 3 Beijing Time. </span><a href="https://medium.com/@QimingVenturePartners/qiming-venture-partners-backed-structure-therapeutics-successfully-debuts-on-nasdaq-3fcadd019ece" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p><strong><span style="font-size:18px;">Financing</span></strong></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Mafengwo</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">, China's largest online traveling community, completed a new round of fundraising. The proceeds will be used to establish supply chain and content system. </span></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Curie.Bio </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">raised $520 million recently. Acting as both a drug discovery copilot and seed investor, Curie.Bio provides biotech startups with seed-stage money plus professional expertise and service of company operation, which lays a solid foundation for a successful series A funding round. </span><a href="https://www.fiercebiotech.com/biotech/weinberg-borisy-launch-new-biotech-vc-offer-drug-discovery-copilots" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Hochuen Medical</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> completed its Series B round of financing worth tens of millions of RMB. Qiming Venture Partners led its Series A round and continued to participate in this round. The funding will be used to accelerate Hochuen's CDMO business expansion in the global market, new technology and process R&amp;D, and overseas capacity expansion.</span></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Oricell Therapeutics</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> announced the closing of its $45M Series B1 round, with continued participation from Qiming Venture Partners. The new injection of capital will be utilized primarily to support the company's core product clinical development in the US.</span><a href="https://www.oricell.com/en/about/news/191.html" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif"> (Read More)</span></b></a></span></span></p>

<p style="text-align:left; margin:0cm"><strong>•&nbsp;&nbsp; &nbsp;</strong><span style="font-size:10.5pt"><span style="font-family:DengXian"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Desano</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> announced the completion of its Pre-IPO round of financing, which is one of the largest private equity financing deals in China's pharmaceutical sector in 2022.</span></span></span></p>

<p><strong><span style="font-size:18px;">Progress</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Roborock</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (SHSE: 688169) launched a molecular sieve all-in-one washer dryer H1 with Zeo-cycle™ molecular sieve low-temperature drying technology. </span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Xiaomi Technology</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (SEHK: 1810) recently introduced its latest breakthrough in AR technology - Xiaomi Wireless AR Glass Discovery Edition and other new products.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">The first public self-driving bus line jointly developed by <b>WeRide</b> in Guangzhou Science City of Guangdong province was officially launched. This innovative experiment of intelligent transportation will provide passengers with a fresh way of commuting. </span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Gan &amp; Lee Pharmaceuticals </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(SHSE: 603087) announced that the first Chinese insulin Biologics License Application (BLA) submission was officially accepted by the US FDA. </span><a href="https://www.ganlee.com/detail/683.html" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">CanSino Biologics</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (SEHK: 6185, SHSE: 688185) announced that <i>Preprints with&nbsp;The Lancet</i> recently published the phase IIb trial results of CanSinoBIO's&nbsp;mRNA&nbsp;COVID-19&nbsp;vaccine&nbsp;CS-2034. The latest study shows encouraging results of CS-2034 as heterologous booster. Additionally, a new study of the sequential booster of CanSinoBIO's inhaled COVID-19 vaccine in children and adolescents shows good safety and efficacy. </span><a href="https://www.cansinotech.com/html/1/179/180/1674.html" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Scientists from <b>Insilico Medicine</b> have published in the <i>Journal of Chemical Information and Modeling</i> on the use of its generative AI Chemistry42 platform to quickly design novel molecular structures that target proteins that play essential roles in disease progression. The company's first anti-fibrotic drug candidate INS018_055 was also granted orphan drug designation (ODD) by the US FDA and its first generative AI-designed drug ISM3312 for COVID-19 and variants received clinical trial approval from China's NMPA. </span><a href="https://www.eurekalert.org/news-releases/978920" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Zai Lab </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(NASDAQ: ZLAB, SEHK: 9688) announced that China's National Medical Products Administration (NMPA) has accepted the New Drug Application (NDA) for sulbactam-durlobactam (SUL-DUR).</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">APT Medical </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(SHSE: 688617) announced the completion of patient enrollment in the premarket clinical trials of its pulsed field ablation (PFA) system. APT Medical obtained Brazil ANVISA (Brazilian Health Regulatory Agency) approval of several peripheral products including adjustable valve guiding sheath, guidewire, balloon occlusion microcatheter, and guiding sheath.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Venus Medtech</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (SEHK: 2500) successfully treated the first VenusP-Valve patient in Poland, which represents another progress in rolling out its technology within Europe. The company also announced that Cardiovalve TR is approved for clinical trials in Spain.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Asieris Pharmaceuticals </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(SHSE: 688176) announced that one of its late-stage investigational drugs, APL-1202, helped UCSF Health, save the life of a man suffering from a rare brain-eating amoeba. The registration applications for its single-use, handheld electronic cystoscope cannula Uro-G and electronic endoscope image processor Uro-3500 were accepted by China's NMPA.</span><a href="https://www.science.org/content/article/repurposed-drug-battles-brain-eating-amoeba" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif"> (Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Abbisko Therapeutics</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (SEHK: 2256) announced that ABSK121, a next-generation small molecule FGFR inhibitor overcoming FGFR resistance mutations, has obtained clinical trial approval from China's NMPA.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Connect Biopharma</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (NASDAQ: CNTB) announced that its CBP-201 Phase 2 global trial in patients with moderate-to-severe asthma with Type 2 inflammation (WW002) has reached its full targeted enrollment.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Shukun Technology </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">obtained NMPA Class III medical device registration certificate of Shukun-FFR, a CT-FFR intelligent assessment system, by China's NMPA.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Beijing has begun inoculating <b>SinocellTech</b> (SHSE: 688520)'s COVID recombinant protein bivalent vaccine SCTV01C, China's first multivalent vaccine that can provide broad-spectrum protection against COVID variants.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Infervision</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> launched its first InferScholar project in Spain, setting a new standard for how healthcare providers can use AI to make an impact on patient outcomes. </span></p>

<p><strong><span style="font-size:18px;">Partnerships</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Several portfolio companies including <b>Zeen Health</b>, <b>AI Prime</b>, <b>DeepWay</b> will be among the first ecological partners of Baidu's Ernie Bot to fully experience and access the abilities of Baidu's leading&nbsp;intelligent&nbsp;dialogue technology.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">LanzaTech</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (NASDAQ: LNZA) announced a collaboration with Abu Dhabi Waste Management Company - Tadweer to develop a large-scale conversion plant for transforming solid municipal waste into sustainable alternative fuel.<b> (</b></span><a href="https://lanzatech.com/lanzatech-and-tadweer-to-explore-collaboration-on-conversion-of-waste-to-alternative-fuels/" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">Read More</span></b></a><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">)</span></b></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Insta360</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> Link, the powerful 4K webcam using AI to redefine remote work, is now certified for Tencent Meeting, becoming the first AI PTZ webcam certified by two major domestic video conference platforms in China. Insta360 has also joined hands with Harley-Davidson Motor Company and is the newest partner of H.O.G (Harley Owners Group) to chronicle motorcycle riders' epic adventures and travel stories.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">GYENNO SCIENCE</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> was selected in Microsoft for Startups' Spring 2023 entrepreneurship accelerator program.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">CanSino Biologics </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(SEHK: 6185, SHSE: 688185) and Solution Biologics Sdn. Bhd. jointly announced that the first bulk shipment of the active pharmaceutical ingredients (APIs) of CanSinoBIO's COVID-19 vaccine (Convidecia<sup>®</sup>) in bulk form has arrived in Malaysia.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Asieris Pharmaceuticals </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(SHSE: 688176) forged a research collaboration and option-to-license agreement with ReviR Therapeutics to discover and develop innovative treatments for genitourinary (GU) tumors and other related serious diseases. </span><a href="https://asieris.com/asieris-and-revir-collaborate-in-oncology-therapeutics-using-rna-targeting-technologies/" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Zencore Biologics</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> signed a strategic partnership agreement with Cobetter to explore and co-develop cutting-edge biological consumables and collaborate closely on brand and product promotion.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">DPTechnology </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">and Jing Medicine, an innovative biotechnology company, announced cooperation to jointly promote the R&amp;D of new small molecule drugs targeting tumors through the combination of AI and physical simulation.</span></p>

<p><strong><span style="font-size:18px;">Global Activity</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Pluslife Biotech</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> participated in the Medlab Middle East 2023, showcasing its innovative eight-channel POC molecular analyzer, integrated nucleic acid testing device Mini Dock, testing cards covering respiratory tract infections, animal diseases, etc. to provide visitors with better molecular POC solutions.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">MicroTech Medical </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(SEHK: 2235) participated in the 2023 Arab Health Exhibition, partnering with regional distributors and KOLs to push the accessibility of continuous glucose monitoring (CGM) and continuous subcutaneous insulin infusion (CSII) and help people with diabetes lead a healthy life.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Frontage Laboratories </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">participated in the Summit for Clinical Ops Executives (SCOPE) Summit 2023.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">NUROTRON </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">participated in the IFOS Dubai - ENT World Congress 2023, presenting its cochlear implants and other products.</span></p>

<p><strong><span style="font-size:18px;">Corporate Development</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">New Horizon Health</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (SEHK: 6606) opened a new R&amp;D center in the HKSTP (Hong Kong Science and Technology Parks). The total investment is expected to be HK$100 million over the next five years. </span><a href="https://www.scmp.com/business/china-business/article/3210476/hangzhou-based-cancer-screening-firm-new-horizon-health-opens-rd-centre-hong-kong-tech-hub-it-eyes?module=perpetual_scroll_0&amp;pgtype=article&amp;campaign=3210476" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">SinoUnited Health</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> opened its sixth clinic in Shanghai - Tianshan Clinic in February 2023. Tianshan Clinic offers a variety of skincare and health screening services with "general practice + specialty" model. </span><a href="https://mp.weixin.qq.com/s/qXxZA9aAmupsujZlMRSG5w" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Lantheus, a Nasdaq-listed company, announced it has acquired Cerveau Technologies, our portfolio company <b>Sinotau Pharmaceuticals</b>' joint venture in the US, with an upfront payment and potential additional development and commercial milestone payments. This acquisition marks an important milestone in the development of molecular imaging.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Hope Medicine </span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">announced that Nathan Chen will serve as Chief Executive Officer and join the board of directors to lead and accelerate the progress of the company's major clinical projects, while focusing on development to ensure that more R&amp;D pipeline products will reach clinical milestones and fully realize the company's strategic goals.</span></p>

<p><strong><span style="font-size:18px;">Insights</span></strong></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Dr. Bowen Zhou, Founder of <b>Frontis </b>analyzed that the improving collaboration between AI and people, as well as interactive learning ability represent the core progress of ChatGPT. He also highlighted the significance of ChatGPT's interaction paradigm in the real-world industry.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">TigerGraph</span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> Founder and CEO Dr. Yu Xu recently shared the company's unique strengths to gain widespread adoption and how TigerGraph steered the database community on the NYSE Floor Talk. </span><a href="https://www.youtube.com/watch?v=akiHskcXalE" style="color:#0563c1; text-decoration:underline"><b><span style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p><strong><span style="font-size:18px;">Awards</span></strong></p>

<p class="1" style="text-align:left"><a name="_Hlk118461642"></a><strong>•&nbsp;&nbsp; &nbsp;</strong><a name="_Hlk118461642"><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">8 Leading AI Drug Discovery Biotechs</span></i></b></a><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>Business Insider</i> - Schrödinger and Insilico Medicine </span><a href="https://www.businessinsider.com/list-top-ai-biotech-companies-recursion-schrodinger-abcellera" style="color:#0563c1; text-decoration:underline"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">(Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">VIGOROUS 100 Ranking List</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>ChinaVenture </i>- Mech-Mind Robotics, Shukun Technology, Tungee, WeRide, Zencore Biologics</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">2022 New Unicorn Companies List</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>Forbes China</i> - ROX Motor, Mech-Mind Robotics, Zencore Biologics, etc.</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">50 Digital Health Companies China</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>DeepTech</i> - Fortune Care, Clinical Decision Support System, Insilico Medicine, Shukun Technology, Infervision, Slan Health and WeDoctor </span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Best Data and AI Product or Technology: Analytics Database (Editor</span></i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">'<i>s Choice)</i></span></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>BigDATAwire </i>– TigerGraph</span><a href="https://www.datanami.com/2022-readers-choice-awards/" style="color:#0563c1; text-decoration:underline"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">The Power 500 Software Companies of 2023</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>Software Report</i> - Schrödinger and TigerGraph</span><a href="https://www.thesoftwarereport.com/the-power-500-software-companies-of-2023/" style="color:#0563c1; text-decoration:underline"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (Read More)</span></b></a></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Second KPMG China Emerging Consumer Brands 50 Report and List</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> – Superhexa</span></p>

<p class="1" style="text-align:left"><strong>•&nbsp;&nbsp; &nbsp;</strong><b><i><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif">Best Places to Work for 2023</span></i></b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> by <i>Built In </i>– Schrödinger</span><a href="https://builtin.com/awards/us/2023/best-places-to-work" style="color:#0563c1; text-decoration:underline"><b><span lang="EN-US" style="font-family:&quot;Calibri&quot;,sans-serif"> (Read More)</span></b></a></p>

<p>&nbsp;</p>

<p><span style="color:#7f8c8d;"><span style="font-size:16px;">Sources: Qiming Venture Partners, company press releases, media reports, etc. </span></span><br />
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